Africa Clinical Research Network (ACRN) is an African-led clinical research organization building the next generation of trial capacity across the continent. We work with existing hospitals, research units, and investigators to enable high-quality clinical research—from investigator-initiated studies to late-phase and registration trials—while strengthening local systems, skills, and infrastructure.
ACRN operates as a pan-African site management and research delivery platform, combining strong clinical operations, regulatory expertise, data and digital systems, and quality management. Our model is practical and embedded: we focus on making trials work in real settings, reducing friction for sites, sponsors, and regulators, and delivering reliable, audit-ready data.
We partner closely with governments, regulators, academic institutions, and industry to expand Africa’s role in global clinical research, while ensuring that studies generate local value—through workforce development, institutional strengthening, and improved patient care.
At ACRN, you’ll work on meaningful, complex projects with global impact, alongside a multidisciplinary team that values rigor, accountability, and innovation. We are building something durable, ambitious, and distinctly African—and we are looking for people who want to help shape it.
About the role
The Clinical Project Manager (IC3) is a senior individual contributor role responsible for the day-to-day operational management and delivery of assigned clinical trials within ACRN’s regulated CRO/SMO environment. Reporting to the Senior Clinical Project Manager (IC4), the role supports end-to-end study execution across one or more countries, ensuring delivery in accordance with ICH-GCP, regulatory requirements, approved protocols, sponsor expectations, and ACRN SOPs.
The IC3 Clinical Project Manager leads cross-functional study teams on a day-to-day basis, coordinates timelines, tracks milestones, manages risks and issues, and supports consistent quality and inspection readiness. The role serves as a key operational interface for sponsors and internal teams, escalating complex issues, budget variances, or strategic risks to the IC4 Project Manager as appropriate.
What you'll do
1. Study Execution and Operational Delivery
• Manage day-to-day execution of assigned clinical trials from start-up through close-out under oversight of the IC4 Project Manager.
• Ensure study activities are delivered according to agreed timelines, scope, and quality standards.
• Support implementation of study management plans and operational strategies.
2. Cross-Functional Team Coordination (Matrixed)
• Coordinate cross-functional contributors including CRAs, Data Management, Regulatory Affairs, Pharmacovigilance, Laboratories, and vendors.
• Ensure clarity of roles, responsibilities, and deliverables across the study team.
• Drive timely follow-up on assigned actions and deliverables.
3. Timeline, Milestone, and Issue Tracking
• Develop and maintain detailed study timelines, trackers, and action logs.
• Monitor progress against milestones and identify delays or risks early.
• Propose mitigation actions and escalate significant risks or dependencies to the IC4 Project Manager.
4. Risk Management and Quality Oversight
• Identify, document, and manage operational, regulatory, and quality risks at study level.
• Support deviation management, CAPA follow-up, and issue resolution in collaboration with Quality and Clinical Operations.
• Ensure study documentation and activities remain inspection-ready at all times.
5. Site Readiness and Performance Support
• Support site selection, initiation readiness, and ongoing site performance monitoring.
• Ensure sites receive appropriate training, resources, and operational support.
• Work closely with CRAs to address site-level challenges and performance issues.
6. Sponsor Communication and Reporting
• Support sponsor communications including routine status updates, metrics reporting, and issue discussions.
• Prepare study status reports, dashboards, and presentations for sponsor and internal review.
• Escalate sponsor concerns, scope changes, or delivery risks to the IC4 Project Manager.
7. Budget and Financial Tracking Support
• Track study spend and resource utilization against approved budgets.
• Flag potential budget variances or scope changes to the IC4 Project Manager.
• Support financial forecasting and reporting activities as required.
8. Monitoring, Audits, and Inspections Support
• Support preparation for monitoring visits, sponsor audits, and regulatory inspections.
• Coordinate study-level responses to monitoring findings and action items.
• Ensure timely closure of findings in collaboration with site and functional teams.
9. Continuous Improvement and Knowledge Sharing
• Contribute to lessons learned, best practices, and process improvements across Clinical Operations.
• Support consistency of project management practices and tools across studies.
Qualifications
Minimum Qualifications
• Bachelor’s degree in Life Sciences, Nursing, Public Health, Pharmacy, or a related field.
Preferred Qualifications
• Advanced degree or certification in clinical research or project management.
Required Experience
• 5–8 years’ experience in clinical research operations.
• Demonstrated experience coordinating or managing clinical trials in regulated environments.
Application Deadline: 27 February 2026
PI483c9696a9c7-37437-39722105
